Key result
Murine norovirus showed similar nucleic acid reduction rates to Norwalk virus (0.04 vs 0.04 log10/day at 25°C), making it a promising surrogate for human norovirus in water.
Population
Surface water samples and groundwater samples spiked with viral surrogates and Norwalk virus
Design
Preclinical
Authors
Loading...
Supports murine norovirus for water modeling; leaves open human infectivity validation.
Murine norovirus shows promise as a surrogate for human norovirus in water persistence models due to its environmental stability, whereas feline calicivirus is less stable and questionable as a surrogate.
Bae et al. (2007) studied Human norovirus persistence in water (n=15). Murine norovirus (MNV), feline calicivirus (FCV), poliovirus (PV), and MS2 vs. Norwalk virus (NV) was evaluated on Nucleic acid reduction rates at 25 degrees C. Murine norovirus showed similar nucleic acid reduction rates to Norwalk virus (0.04 vs 0.04 log10/day at 25°C), making it a promising surrogate for human norovirus in water.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: