Key result
A newly developed Hodgkin Huxley Kelvin-like model successfully accounted for the effect of the surrounding viscoelastic medium on current flow and stimulation in cardiac muscle fibers.
Why the study?
Previous Hodgkin Huxley models did not account for the surrounding medium in which cardiac muscles are immersed or its effect on current flow.
Incorporating a viscoelastic medium into the Hodgkin Huxley model improves the simulation of current flow and mechanical properties in cardiac muscle fibers.
Requires prospective validation before clinical use; leaves open the effect of surrounding medium on cardiac conduction.
In the present work the author incorporated the surrounding medium with Hodgkin Huxley model to account the effect of surroundings on the flow of current in cardiac muscles fibers. The Hodgkin Huxley Kelvin like model is developed here and then the governing equations are solved by appropriate mathematical methods and the obtained results are compared with the previous experimental findings. Through obtained solutions, we check the mechanical properties in actual environment of cardiac muscles fibres and compare our findings with experimental results. Previous Hodgkin Huxley model did not give any idea about the medium, in which the cardiac muscles are immersed. The new developed model accounts the effect of medium efficiently on the current flow along with fiber's stimulation in cardiac muscles.
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Taj et al. (2021) studied Cardiac muscle fiber modeling. Hodgkin Huxley Kelvin like model vs. Previous Hodgkin Huxley model was evaluated. A newly developed Hodgkin Huxley Kelvin-like model successfully accounted for the effect of the surrounding viscoelastic medium on current flow and stimulation in cardiac muscle fibers.
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