Key result
In a patient with chronic thromboembolic pulmonary hypertension, pulmonary thromboembolectomy resulted in more significant immediate recovery of LV diastolic function than RV systolic function.
Why the study?
Does pulmonary thromboembolectomy improve biventricular function immediately post-bypass in a patient with chronic thromboembolic pulmonary hypertension?
Case Report (n=1)
Does pulmonary thromboembolectomy improve biventricular function immediately post-bypass in a patient with chronic thromboembolic pulmonary hypertension?
In a patient with CTPH, geometrically altered LV recovers more rapidly than the hypertrophied and hypokinetic RV immediately following pulmonary thromboembolectomy.
May indicate faster LV than RV recovery post-thromboembolectomy in CTEPH; hypothesis-generating and should not yet change practice.
Postoperative studies in patients with chronic thromboembolic pulmonary hypertension (CTPH) have shown that pulmonary thromboembolectomy (PTE) results in a rapid decrease of right ventricular (RV) size, improvement in the RV systolic function and left ventricular (LV) diastolic function. However, the extent to which the biventricular function recovers immediately after embolectomy in post-cardiopulmonary bypass period is not clear. A 45-year-old male patient was operated for retrieval of thrombus from pulmonary trunk and right pulmonary artery. Intraoperative transesophageal echocardiography (TOE) before surgery revealed signs of RV dysfunction and enlargement. The interventricular septum was seen moving paradoxically during end-systole and early-diastole. E/A ratio on transmitral Doppler flow velocity profile was about 0.63 and S/D ratio on pulmonary venous Doppler profile was 2.25, indicative of LV diastolic dysfunction. After weaning the patient from bypass, navigation on TOE showed marginal recovery of the RV systolic function and abatement of septal paradox to some extent. However, significant improvement was observed in the LV diastolic parameter (normal E/A ratio, S/D ratio of 1.08). We conclude that the geometrically altered LV recovers more than the hypertrophied and hypokinetic RV in a patient with CTPH in the post-bypass period.
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Gadhinglajkar et al. (2009) conducted a case report in Chronic thromboembolic pulmonary hypertension (n=1). Pulmonary thromboembolectomy vs. Pre-operative state was evaluated on Biventricular function recovery (RV systolic and LV diastolic function). In a patient with chronic thromboembolic pulmonary hypertension, pulmonary thromboembolectomy resulted in more significant immediate recovery of LV diastolic function than RV systolic function.
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