Key result
Simultaneous gradient-echo and spin-echo imaging showed that the ratio of relaxation rates (deltaR2*/deltaR2) was lower during reactive hyperemia relative to ischemia in human skeletal muscle.
Why the study?
Does simultaneous gradient-echo/spin-echo EPI provide temporal and spatial information about skeletal muscle perfusion during graded ischemia?
Observational
Does simultaneous gradient-echo/spin-echo EPI provide temporal and spatial information about skeletal muscle perfusion during graded ischemia?
Simultaneous GE/SE EPI imaging can measure changes in relaxation rates during ischemia and reactive hyperemia, potentially providing a measure of the relative distribution of small and large vessels in skeletal muscle.
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May differentiate vessel-size contributions in muscle perfusion; leaves open clinical utility of GE/SE EPI for ischemia grading.
Donahue et al. (1998) conducted an observational in graded ischemia in human skeletal muscle. Simultaneous gradient-echo/spin-echo EPI was evaluated on change in GE and SE relaxation rates (deltaR2*, deltaR2). Simultaneous gradient-echo and spin-echo imaging showed that the ratio of relaxation rates (deltaR2*/deltaR2) was lower during reactive hyperemia relative to ischemia in human skeletal muscle.
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