Key result
Myocardial contractility in women appears to be better preserved after the age of 50 years compared with that in men.
Why the study?
How do age and sex affect myocardial contractility in middle-aged subjects when assessed using different normalization methods for end-systolic elastance?
Cross-Sectional (n=2,184)
How do age and sex affect myocardial contractility in middle-aged subjects when assessed using different normalization methods for end-systolic elastance?
Myocardial contractility appears better preserved in women than men after age 50, though the choice of normalization method for end-systolic elastance significantly impacts the assessment of sex differences.
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Novel E(es) normalization may enable geometry-independent LV contractility comparisons; leaves open prospective validation before clinical adoption.
Claessens et al. (2006) conducted a cross-sectional in Free from overt cardiovascular disease (n=2,184). Female sex vs. Male sex was evaluated on Myocardial contractility. Myocardial contractility in women appears to be better preserved after the age of 50 years compared with that in men.
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