Key result
Shortening of atrioventricular delay at increased atrial paced heart rates significantly improved diastolic filling time by 14% (mean difference 40.2 ms) compared to a fixed AV delay.
Why the study?
Does shortening of atrioventricular delay at increased atrial paced heart rates improve diastolic filling and functional class in patients with biventricular pacing?
Observational (n=34)
No
Does shortening of atrioventricular delay at increased atrial paced heart rates improve diastolic filling and functional class in patients with biventricular pacing?
Mean Difference: 40.2
Absolute Event Rate: 318% vs 279%
p-value: p=<0.001
Aggressive AV delay shortening at increased heart rates in patients with biventricular pacing improves diastolic filling and short-term functional class.
Authors
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Shortened AV delay may improve diastolic filling at higher rates in Biv-paced patients; leaves open whether rate-adaptive programming affects clinical outcomes.
Rafie et al. (2012) conducted an observational in Heart failure with biventricular pacing (n=34). Shortened atrioventricular (AV) delay vs. Fixed AV delay was evaluated on Diastolic filling time at increased atrial pacing rates (MD 40.2 ms, p=<0.001). Shortening of atrioventricular delay at increased atrial paced heart rates significantly improved diastolic filling time by 14% (mean difference 40.2 ms) compared to a fixed AV delay.
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