Key result
In a nationwide survey of Japanese patients with hypertension, 31.6% expressed a preference for renal denervation, with younger age, male sex, higher blood pressure, and drug side effects as significant predictors.
Why the study?
Data on patient preference for renal denervation as an alternative to antihypertensive drug therapy were limited, with no data specifically from Asian patients.
What is the prevalence and what are the predictors of patient preference for renal denervation among Japanese patients with hypertension?
Cross-Sectional (n=2,392)
What is the prevalence and what are the predictors of patient preference for renal denervation among Japanese patients with hypertension?
Nearly one-third of Japanese patients with hypertension expressed a preference for renal denervation, suggesting patient preference should be incorporated into shared decision-making for hypertension management.
Answers are grounded in this paper and cite their sources.
Nearly one-third of Japanese patients prefer renal denervation; supports shared decision-making but leaves practice change open pending higher-level evidence.
Renal denervation is a potential alternative to antihypertensive drug therapy. However, data on patient preference for this treatment option are limited and there are no data specifically from Asian patients. This study evaluated patient preference for renal denervation in patients with hypertension from Japan. Patients were a subset of those who participated in a March 2020 online electronic survey of patients with hypertension who had regularly visited medical institutions for treatment, were receiving antihypertensive drug therapy and had home blood pressure recordings available. The survey included a question about patient preference for treatment with renal denervation. A total of 2,392 patients were included (66% male, mean age 59.8 ± 11.6 years, mean duration of hypertension 11.4 ± 9.5 years). Preference for renal denervation was expressed by 755 patients (31.6%), and was higher in males than in females, in younger compared with older patients, in those with higher versus lower blood pressure, in patients who were less adherent versus more adherent to antihypertensive drug therapy, and in those who did rather than did not have antihypertensive drug-related side effects. Significant predictors of preference for renal denervation on logistic regression analysis were younger patient age, male sex, higher home or office systolic blood pressure, poor antihypertensive drug adherence, the presence of heart failure, and the presence of side effects during treatment with antihypertensive drugs. Overall, a relevant proportion of Japanese patients with hypertension expressed a preference for renal denervation. This should be taken into account when making shared decisions about antihypertensive drug therapy.
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Kario et al. (2021) conducted a cross-sectional in Hypertension (n=2,392). Renal denervation (patient preference) was evaluated on Preference for renal denervation. In a nationwide survey of Japanese patients with hypertension, 31.6% expressed a preference for renal denervation, with younger age, male sex, higher blood pressure, and drug side effects as significant predictors.
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