What is the clinical evidence from this study?

Study design: Cohort. Population: Hemodialysis (n=369). Intervention: End-expiration inferior vena cava (IVC) diameter. Primary outcome: Prevalence and control of hypertension.

What question did this study set out to answer?

This research aims to accurately describe the epidemiology of hypertension and its correlates in hemodialysis patients.

January 1, 2011American Journal of NephrologyOpen Access

Epidemiology of Interdialytic Ambulatory Hypertension and the Role of Volume Excess

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Key result

End-expiration inferior vena cava diameter was associated with an increased risk of poorly controlled hypertension among hemodialysis patients, where hypertension was prevalent in 82%.

Why the study?

What is the prevalence of interdialytic ambulatory hypertension and its association with volume excess in hemodialysis patients?

Population

369 hemodialysis patients

Design

Cross-sectional

Follow-up

44 hours

Authors

RARajiv AgarwalHeart Failure & Transplant

Discussion

Member takes

Implication

Interdialytic ABPM shows high hypertension prevalence in HD; leaves open optimal volume-targeted management strategies.

Key Points

This research aims to accurately describe the epidemiology of hypertension and its correlates in hemodialysis patients.
Analyzed 44-hour interdialytic ambulatory blood pressure measurements in a cohort of 369 patients.
Withdrew antihypertensive agents from patients with controlled hypertension and repeated BP monitoring.
Used IVC diameter measurements to assess correlations with hypertension control.
Hypertension was present in 82% of the patients, correlated with epoetin use, lower BMI, and fewer years on dialysis.
Only 38% of patients had adequately controlled hypertension despite treatment in 89% of cases.
IVC diameter in expiration was linked to the risk of poorly controlled hypertension.

Study Design

Type

Cohort (n=369)

Structured PICO

What is the prevalence of interdialytic ambulatory hypertension and its association with volume excess in hemodialysis patients?

Population

369 hemodialysis patients assessed for interdialytic ambulatory hypertension and its correlation with volume excess.

Exposure

44-hour interdialytic ambulatory blood pressure monitoring and withdrawal of antihypertensive agents among patients with controlled hypertension

Outcome

Prevalence and control of hypertension (defined as average ambulatory systolic BP ≥135 mm Hg or diastolic BP ≥85 mm Hg, or use of antihypertensive medications) and its correlatessurrogate

Interdialytic hypertension is highly prevalent and poorly controlled in hemodialysis patients, with volume excess (indicated by IVC diameter) being a significant contributing factor.

Cite This Study

Rajiv Agarwal (2011) conducted a cohort in Hemodialysis (n=369). End-expiration inferior vena cava (IVC) diameter was evaluated on Prevalence and control of hypertension. End-expiration inferior vena cava diameter was associated with an increased risk of poorly controlled hypertension among hemodialysis patients, where hypertension was prevalent in 82%.

synapsesocial.com/papers/6a6a48c856128ae23fcb1cf7 https://doi.org/10.1159/000331067

Topics

Hypertension management

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Epidemiology of Interdialytic Ambulatory Hypertension and the Role of Volume Excess

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Epidemiology of Interdialytic Ambulatory Hypertension and the Role of Volume Excess

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider