Key result
Hypertension and aging have opposing effects on arterial distensibility, with hypertension-associated structural changes increasing distensibility and aging decreasing it.
Design
Review
Authors
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Supports considering compensatory distensibility effects in older hypertensives; leaves open prospective validation of opposing mechanisms.
Hypertension-induced arterial wall hypertrophy may be a compensatory mechanism to maintain distensibility despite increased pressure, contrasting with the stiffening effects of aging.
Laurent et al. (1996) conducted a review in Hypertension and aging. Hypertension and aging was evaluated on Arterial distensibility and structural changes. Hypertension and aging have opposing effects on arterial distensibility, with hypertension-associated structural changes increasing distensibility and aging decreasing it.
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