Key result
Excessive length of stay after esophagectomy independently predicted higher overall mortality (OR 1.56; 95% CI 1.46-1.67), reducing median survival from 53.6 to 30.6 months (P<0.0001).
Why the study?
Complications after esophagectomy impact short-term survival, but the specific effect of prolonged length of stay on long-term survival is unclear.
Does excessive length of stay (as a surrogate for postoperative complications) reduce long-term survival in patients undergoing esophagectomy who survive at least 90 days?
Population
20,719 patients undergoing esophagectomy surviving at least 90 days postoperatively
Comparison
Excessive length of stay (highest quintile) vs non-excessive length of stay
Design
Retrospective database cohort study
Authors
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Prolonged LOS may mark higher long-term mortality after esophagectomy; leaves open whether complications drive outcomes in prospective data.
Cohort (n=20,719)
Yes
Does excessive length of stay (as a surrogate for postoperative complications) reduce long-term survival in patients undergoing esophagectomy who survive at least 90 days?
Odds Ratio: 1.56 (95% CI 1.46–1.67)
p-value: p=< 0.0001
Excessive length of stay after esophagectomy, indicative of postoperative complications, is an independent predictor of reduced long-term survival even among patients who survive the initial 90-day postoperative period.
Sachidananda et al. (2021) conducted a cohort in Esophagectomy (n=20,719). Excessive length of stay (ELOS) vs. Non-ELOS was evaluated on overall mortality (OR 1.56, 95% CI 1.46-1.67, p=< 0.0001). Excessive length of stay after esophagectomy independently predicted higher overall mortality (OR 1.56; 95% CI 1.46-1.67), reducing median survival from 53.6 to 30.6 months (P<0.0001).