Key result
Adenosine elicited a rhythm response in 90% of supraventricular tachycardia patients versus 2% of ventricular tachycardia patients, increasing the odds of SVT by a factor of 36 (95% CI 9-143).
Why the study?
Does adenosine infusion safely diagnose and treat undifferentiated wide QRS complex tachycardia in emergency settings?
Observational (n=197)
Yes
Does adenosine infusion safely diagnose and treat undifferentiated wide QRS complex tachycardia in emergency settings?
Odds Ratio: 36 (95% CI 9–143)
Absolute Event Rate: 90% vs 2%
Adenosine is a safe and useful diagnostic and therapeutic agent for differentiating and treating regular wide QRS complex tachycardia.
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Adenosine may aid diagnosis and termination in stable regular wide QRS tachycardia; retrospective data leave open need for prospective trials.
Marill et al. (2009) conducted an observational in regular wide QRS complex tachycardia (n=197). Adenosine infusion vs. Ventricular tachycardia was evaluated on Rhythm response to adenosine (OR 36, 95% CI 9-143). Adenosine elicited a rhythm response in 90% of supraventricular tachycardia patients versus 2% of ventricular tachycardia patients, increasing the odds of SVT by a factor of 36 (95% CI 9-143).
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