Key result
Human endogenous retrovirus genes (HERV-K) were cloned from a fetal human liver gene library, showing typical retrovirus LTR features and an estimated 50 copies per haploid human genome.
Population
Fetal human liver gene library
Design
Preclinical
Authors
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No immediate clinical implications; leaves open HERV-K roles in human disease for future study.
The study successfully cloned and characterized human endogenous retrovirus genes (HERV-K), revealing typical retroviral structural features and estimating their copy number in the human genome.
Masahiro Ono (1986) studied this question. Human endogenous retrovirus genes (HERV-K) were cloned from a fetal human liver gene library, showing typical retrovirus LTR features and an estimated 50 copies per haploid human genome.
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