Treatment of Subacute Bacterial Endocarditis: Current Results

Article1 November 1943TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITIS: CURRENT RESULTSS. S. LICHTMAN, M.D., F.A.C.P.S. S. LICHTMAN, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-19-5-787 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSulfonamide chemotherapy has proved disappointing in subacute bacterial endocarditis. Final judgment of its merit must be reserved, however, until the incidence of recovery in a large series of treated cases is compared with spontaneous recovery in the pre-sulfonamide era.In a preliminary survey of 288 cases of subacute bacterial endocarditis treated by current methods, Lichtman and Bierman1 deduced that chemotherapy and supplementary measures produced recovery in a small but significant percentage of cases. This survey has been continued with the aim of obtaining correct answers to the questions:1. 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Y.*Received for publication August 17, 1942.From the Medical Services, The Mount Sinai Hospital. Based on material presented at the Scientific Exhibit, Symposium on Cardiovascular Disease, Annual Session, American Medical Association, Atlantic City, June 8-12, 1942.†This is arbitrarily fixed at a minimum of two weeks of intensive sulfonamide medication; seven artificial hyperthermia treatments, six intravenous injections of typhoid vaccine, and heparinization for two weeks with a blood coagulation time of one hour, respectively.‡Two private cases treated by Drs. E. P. Boas and Elmer Gais, respectively, recovered and are included with their kind permission. Cases are regarded as recoveries when they are afebrile and repeated blood cultures are negative for a minimum period of three months after the use of sulfonamides has been discontinued. 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Conner Lecture of the American Heart AssociationTHE TREATMENT OF BACTERIAL ENDOCARDITIS*EDWARD S. ORGAIN, M.D., F.A.C.P., CHARLES K. DONEGAN, M.D.Revised Criteria for Diagnosis and Treatment of Subacute Bacterial EndocarditisEndocarditis due to hemophilus influenzaeSome recent advances in cardiologyStreptomycin Treatment of Bacterial EndocarditisExperiences in the management of subacute bacterial endocarditis treated with penicillinSulfonamide therapy of subacute bacterial endocarditisSubacute bacterial endocarditis in the aged 1 November 1943Volume 19, Issue 5Page: 787-794KeywordsBlood coagulationCardiovascular diseasesChemotherapyEndocarditisHyperthermiaIntravenous injectionsMedical servicesSulfonamideTyphoidVaccines ePublished: 1 December 2008 Issue Published: 1 November 1943 PDF downloadLoading ...