Key result
The Ultimaster biodegradable-polymer sirolimus-eluting stent demonstrated an excellent efficacy and safety profile with similar clinical outcomes to contemporary, new-generation DES.
Why the study?
Does the Ultimaster biodegradable-polymer sirolimus-eluting stent provide similar efficacy and safety compared to contemporary new-generation DES in patients undergoing coronary stenting?
Does the Ultimaster biodegradable-polymer sirolimus-eluting stent provide similar efficacy and safety compared to contemporary new-generation DES in patients undergoing coronary stenting?
The Ultimaster biodegradable-polymer sirolimus-eluting stent demonstrates comparable efficacy and safety to contemporary new-generation drug-eluting stents.
May support Ultimaster across lesion subsets; extends CENTURY data but leaves comparative effectiveness open.
The Ultimaster coronary stent system (Terumo Corporation, Tokyo, Japan) represents a new iteration in drug-eluting stent (DES) technology that has recently received the Conformité Européenne (CE) mark approval for clinical use. The Ultimaster is a thin-strut, cobalt chromium, biodegradable-polymer, sirolimus-eluting coronary stent. The high elasticity of the biodegradable-polymer (PDLLA-PCL) and the abluminal gradient coating technology are additional novel features of this coronary device. The Ultimaster DES has undergone extensive clinical evaluation in two studies: The CENTURY I and II trials. Results from these two landmark studies suggested an excellent efficacy and safety profile of the Ultimaster DES across several lesion and patient subsets, with similar clinical outcomes to contemporary, new-generation DES. The aim of this review is to summarize the rationale behind this novel DES technology and to provide an update of available evidence about the clinical performance of the Ultimaster DES.
No takes yet. Share an insight, caveat, or question.
Chisari et al. (2016) conducted a review in Coronary artery disease. Ultimaster Biodegradable-Polymer Sirolimus-Eluting Stent vs. Contemporary, new-generation DES was evaluated. The Ultimaster biodegradable-polymer sirolimus-eluting stent demonstrated an excellent efficacy and safety profile with similar clinical outcomes to contemporary, new-generation DES.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: