Key result
Ibutilide converted atrial fibrillation in 55% of patients, with higher success in those with coronary artery disease (77% vs 46%, p=0.005) and without mitral valve disease or enlarged left atrium.
Why the study?
What are the clinical and echocardiographic predictors of successful cardioversion of atrial fibrillation with ibutilide?
Population
101 patients with recent onset atrial fibrillation (≥ 24 h duration)
Design
Cohort
Authors
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Ibutilide may succeed more often in CAD without mitral valve disease; leaves open prospective validation before guiding selection.
Observational (n=101)
What are the clinical and echocardiographic predictors of successful cardioversion of atrial fibrillation with ibutilide?
Ibutilide is most effective for cardioversion of atrial fibrillation in patients with coronary artery disease and those without mitral valve disease or markedly enlarged left atrium.
Das et al. (2002) conducted an observational in Atrial fibrillation (n=101). Ibutilide was evaluated on Conversion to sinus rhythm. Ibutilide converted atrial fibrillation in 55% of patients, with higher success in those with coronary artery disease (77% vs 46%, p=0.005) and without mitral valve disease or enlarged left atrium.
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