Key result
Flecainide achieved a significantly higher rate of conversion to sinus rhythm compared to procainamide (92% vs 65%, P<0.001) in patients with acute atrial fibrillation.
Why the study?
Does flecainide improve conversion to sinus rhythm compared to procainamide in patients with acute recent-onset atrial fibrillation?
RCT (n=80)
Cross-over
Does flecainide improve conversion to sinus rhythm compared to procainamide in patients with acute recent-onset atrial fibrillation?
Absolute Event Rate: 92% vs 65%
p-value: p=< 0.001
Flecainide is significantly more effective than procainamide for the acute cardioversion of recent-onset atrial fibrillation.
Authors
No takes yet. Share an insight, caveat, or question.
May favor flecainide over procainamide for acute AF conversion; leaves open need for larger confirmatory trials.
Madrid et al. (1993) conducted an RCT in Acute atrial fibrillation (n=80). Flecainide vs. Procainamide was evaluated on Conversion to sinus rhythm (p=< 0.001). Flecainide achieved a significantly higher rate of conversion to sinus rhythm compared to procainamide (92% vs 65%, P<0.001) in patients with acute atrial fibrillation.
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