Key result
In children with Kawasaki disease undergoing CABG with a radial artery graft, no cardiovascular-related complications occurred during a follow-up of 0.2 to 5.8 years.
Why the study?
The early clinical outcomes of using radial artery grafts for CABG surgery in children with coronary sequelae of Kawasaki disease were investigated.
What are the early clinical outcomes of using radial artery grafts for CABG in children with Kawasaki disease?
Observational (n=26)
No
What are the early clinical outcomes of using radial artery grafts for CABG in children with Kawasaki disease?
Using radial artery grafts for CABG in children with severe coronary sequelae of Kawasaki disease appears safe, with good early patency and preserved forearm function.
RA grafts show good early patency in pediatric KD CABG; leaves open long-term durability and practice change.
INTRODUCTION: To investigate the early clinical outcomes of using radial artery (RA) graft for coronary artery bypass graft (CABG) surgery in children with coronary sequelae of Kawasaki disease (KD). METHODS: Clinical data of all 26 children (22 male, 4 female) with coronary sequelae of KD who underwent CABG with RA graft at our hospital between March 2016 and September 2023 were retrospectively analyzed. The severity of coronary artery lesions was classified as Va or Vb in all patients. RESULTS: The median (P25, P75) age of patients was 8.5 (6.0, 11.3) y and the median weight was 33.0 (21.0, 45.3) kg. The mean interval from diagnosis to operation was 5.4 ± 3.7 y. The median postoperative mechanical ventilation time was 6.0 (4.0, 12.3) h. The median intensive care unit stay was 2.0 (2.0, 3.3) d. The median length of postoperative hospital stay was 19.0 (13.0, 29.0) d. Postoperative follow-up time ranged from 0.2 to 5.8 y, and no cardiovascular-related complications occurred. Sixteen patients underwent cardiac catheterization or CT angiography during follow-up. One patient each had anastomotic stenosis in RA and right internal thoracic artery graft, respectively, while myocardial perfusion imaging showed no worsening of myocardial ischemia. There was no significant difference in forearm motor and sensory function between the operated and the contralateral arm; brachial artery angiography showed well-established forearm collateral vessels. CONCLUSIONS: CABG is a safe and effective treatment for KD with severe coronary lesions in children. The RA graft has good early patency without impairing forearm function. Individualized surgical and anticoagulant strategies may help improve the prognosis.
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Liu et al. (2025) conducted an observational in Kawasaki disease with coronary sequelae (n=26). Radial artery graft for coronary artery bypass graft (CABG) was evaluated on Cardiovascular-related complications. In children with Kawasaki disease undergoing CABG with a radial artery graft, no cardiovascular-related complications occurred during a follow-up of 0.2 to 5.8 years.
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