Key result
Compared with FDG-PET as a reference, CMR oedema imaging had low sensitivity (33.3%) and 77% specificity for detecting myocardial inflammation in patients with cardiac sarcoidosis.
Why the study?
Cardiac sarcoidosis can present with cardiac arrest or life-threatening arrhythmias, but data on advanced imaging patterns in this subgroup are limited.
What are the advanced imaging patterns on CMR and FDG-PET in patients with cardiac sarcoidosis presenting with cardiac arrest or life-threatening arrhythmias?
Population
60 patients with definite or probable/possible cardiac sarcoidosis presenting with cardiac arrest or life-threatening arrhythmias
Design
Single-centre retrospective imaging database study
Authors
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Variable CMR/PET patterns in CS arrest highlight diagnostic uncertainty; leaves open prospective validation of criteria.
Observational (n=60)
No
What are the advanced imaging patterns on CMR and FDG-PET in patients with cardiac sarcoidosis presenting with cardiac arrest or life-threatening arrhythmias?
Absolute Event Rate: 33.3% vs 77.6%
In patients with cardiac sarcoidosis presenting with life-threatening arrhythmias, LGE frequently involves the basal anteroseptum and RV side of the septum, and FDG-PET is more sensitive than CMR for detecting myocardial inflammation.
Hatipoğlu et al. (2023) conducted an observational in Cardiac sarcoidosis presenting with cardiac arrest or life-threatening arrhythmias (n=60). Cardiovascular magnetic resonance (CMR) oedema imaging vs. 18-fluorodeoxyglucose (FDG) positron emission tomography (PET) was evaluated on Detection of myocardial inflammation. Compared with FDG-PET as a reference, CMR oedema imaging had low sensitivity (33.3%) and 77% specificity for detecting myocardial inflammation in patients with cardiac sarcoidosis.
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