Key result
Overlapping phenotypes in non-ischemic cardiomyopathies were strongly associated with impaired systolic function (OR 7.8; 95% CI 3.4-17.6; p<0.001) and the presence of late gadolinium enhancement.
Population
127 patients from a cardiac magnetic resonance imaging database.
Design
Cross-sectional
Authors
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Association between LV dilatation phenotypes and LGE in non-ischemic cardiomyopathy is hypothesis-generating; prospective validation required before clinical use.
Observational (n=127)
Odds Ratio: 7.8 (95% CI 3.4–17.6)
p-value: p=<0.001
In non-ischemic cardiomyopathies, overlapping phenotypes are associated with greater left ventricular dilatation, worse systolic function, and a higher prevalence of late gadolinium enhancement.
Boban et al. (2018) conducted an observational in Non-ischemic cardiomyopathies with dilated left ventricle (n=127). Overlapping phenotypes vs. Controls was evaluated on Impairment of systolic function (OR 7.8, 95% CI 3.4-17.6, p=<0.001). Overlapping phenotypes in non-ischemic cardiomyopathies were strongly associated with impaired systolic function (OR 7.8; 95% CI 3.4-17.6; p<0.001) and the presence of late gadolinium enhancement.
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