Key result
In adult guinea pig myocardium, the volume fraction of the ventricular transverse-axial tubular system is 2.5-3.2%, while the sarcoplasmic reticulum volume fraction is 10-11% in atria and ~8% in ventricles.
Morphometric analysis reveals that guinea pig ventricular cells have highly developed membrane systems compared to structurally primitive atrial cells.
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Offers initial quantitative TATS/SR data in guinea pig heart; leaves open human translation and clinical relevance.
Forbes et al. (1988) studied Guinea pig myocardium. In adult guinea pig myocardium, the volume fraction of the ventricular transverse-axial tubular system is 2.5-3.2%, while the sarcoplasmic reticulum volume fraction is 10-11% in atria and ~8% in ventricles.
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