January 1, 1980Cells Tissues Organs

Quantitative studies on the ultrastructural differentiation and growth of mammalian cardiac muscle cells

Q: What is the clinical evidence from this study?

Study design: Other. Intervention: Pre- and postnatal developmental periods vs. Rat development. Primary outcome: Ultrastructural differentiation and growth of myocardial cells.

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Key result

Ultrastructural differentiation of guinea pig myocardial cells showed major changes during the last prenatal week, corresponding to the 10th to 20th postnatal day in rats.

Authors

RHReiji HirakowSaitama Medical University TGTadashi GotohOtsu Red Cross Hospital

Discussion

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Implication

Refines interspecies myocardial maturation timelines; leaves open human translational relevance.

PICO

Population

Guinea pigs examined at copulation ages of 50, 57, 64, 73, and 80 days to study myocardial cell ultrastructural differentiation compared to rats.

Exposure / Comparator

Pre- and postnatal developmental periods vs Rat development

Primary Outcome

Ultrastructural differentiation and growth of myocardial cells

Cite This Study

Hirakow et al. (1980) studied this question. Pre- and postnatal developmental periods vs. Rat development was evaluated on Ultrastructural differentiation and growth of myocardial cells. Ultrastructural differentiation of guinea pig myocardial cells showed major changes during the last prenatal week, corresponding to the 10th to 20th postnatal day in rats.

synapsesocial.com/papers/6a6a96f7c068f641bcf40863 https://doi.org/10.1159/000145304

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Quantitative studies on the ultrastructural differentiation and growth of mammalian cardiac muscle cells

Discussion

Member takes

Implication

PICO

Cite This Study

Quantitative studies on the ultrastructural differentiation and growth of mammalian cardiac muscle cells

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider