Key result
Administration of the endothelin antagonist bosentan resulted in complete resolution of life-threatening symptoms in a woman with refractory vasospastic angina.
Why the study?
Does bosentan improve symptoms in a patient with refractory vasospastic angina?
Population
1 woman with profound coronary spasm resulting in life-threatening symptoms, refractory to commonly used…
Design
Case_report
Authors
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Hypothesis-generating for bosentan in refractory vasospastic angina; randomized trials needed before clinical adoption.
Case Report (n=1)
Does bosentan improve symptoms in a patient with refractory vasospastic angina?
Bosentan may be an effective novel therapy for patients with severe, refractory vasospastic angina.
Krishnan et al. (2010) conducted a case report in Refractory Vasospastic Angina (n=1). Bosentan vs. Commonly used anti-anginals was evaluated on Resolution of symptoms. Administration of the endothelin antagonist bosentan resulted in complete resolution of life-threatening symptoms in a woman with refractory vasospastic angina.
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