Key result
The hypertriglyceridemic waist phenotype was associated with metabolic alterations and excess visceral adipose tissue, with 82% of affected individuals having 3 or more cardiovascular risk factors.
Why the study?
Is the hypertriglyceridemic waist phenotype associated with metabolic disorders and visceral fat in adults?
Cross-Sectional (n=191)
Is the hypertriglyceridemic waist phenotype associated with metabolic disorders and visceral fat in adults?
The hypertriglyceridemic waist phenotype is strongly associated with metabolic alterations and excess visceral adipose tissue, suggesting its utility as a simple clinical marker for cardiovascular risk.
Hypertriglyceridemic waist may flag clustered cardiometabolic risks; leaves open its added value for risk stratification.
OBJECTIVE: To evaluate the association of Hypertriglyceridemic waist with metabolic disorders and visceral fat in adults. METHODS: Cross-sectional study with 191 individuals of both sexes. Subjects were grouped according to Waist Circumference (WC) ratings (Men: > 90 cm; Women: > 80 cm) and triglycerides (TG) (> 150 mg/dl) in Group 1 (HTW Phenotype): elevated WC and TG; Group 2 (absence of HTW Phenotype): elevated WC and normal TG or normal WC and elevated TG or normal WC and TG. Metabolic alternations, visceral adipose tissue (VAT) and visceral/subcutaneous fat index (VF/SF) measured by computed tomography were evaluated as cardiovascu - lar risk factors between the groups. RESULTS: Individuals with HTW phenotype, 82% had three or more cardiovascular risk factors. The association between cardiovascular risk factors with HTW phenotype revealed that among men 73.7% had hypercholesterolemia, 94.9% elevated non-HDLc and 78.9% excess of VAT area (p = 0.001). Among women, 65% had elevated Sistolic Blood Plessure, 80% hypercholesterolemia and 90% elevated non-HDLc (p < 0.02). CONCLUSION: The HTW phenotype associated with the metabolic alternations and VAT excess. Individuals with HTW had higher number of cardiovascular risk factors. The Hypertriglyceridemic waist can be used in clinical practice for investigating cardiovascular risk and visceral adipose tissue in individuals.
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Oliveira et al. (2014) conducted a cross-sectional in Metabolic disorders and visceral fat (n=191). Hypertriglyceridemic waist (HTW) phenotype vs. Absence of HTW phenotype was evaluated on Metabolic alterations, visceral adipose tissue (VAT) and visceral/subcutaneous fat index. The hypertriglyceridemic waist phenotype was associated with metabolic alterations and excess visceral adipose tissue, with 82% of affected individuals having 3 or more cardiovascular risk factors.
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