Key result
A non-overt DIC score of 5 or greater was associated with a 28-day mortality rate of 78%, compared to 29% for scores below 5.
Why the study?
Does a non-overt DIC score of 5 or greater predict overt DIC and 28-day mortality in ICU patients?
Population
516 consecutive patients admitted to a university hospital intensive care unit.
Comparison
Non-overt DIC scoring template (score ≥ 5) vs Non-overt DIC score < 5
Design
Cohort
Follow-up
28 days
Authors
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Non-overt DIC template feasible in ICU; hypothesis-generating for prognosis, requires prospective validation.
Cohort (n=516)
No
Does a non-overt DIC score of 5 or greater predict overt DIC and 28-day mortality in ICU patients?
Absolute Event Rate: 78% vs 29%
A non-overt DIC score of 5 or greater is highly prognostic for 28-day mortality in ICU patients and is recommended for diagnosing non-overt DIC.
Toh et al. (2005) conducted a cohort in Non-overt disseminated intravascular coagulation (DIC) (n=516). Non-overt DIC score ≥ 5 vs. Non-overt DIC score < 5 was evaluated on 28-day mortality. A non-overt DIC score of 5 or greater was associated with a 28-day mortality rate of 78%, compared to 29% for scores below 5.
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