Key result
In patients newly treated with amiodarone, the overall incidence rate of adverse drug reactions was 13.91 cases per 100 person-years over a mean follow-up of 38 months.
Why the study?
What is the incidence rate of adverse drug reactions in patients newly treated with amiodarone during long-term follow-up?
Population
98 French outpatients newly treated with amiodarone (57 men, 41 women, mean age 72.6 years)
Design
Cohort
Follow-up
mean 38 months
Authors
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Amiodarone ADR incidence in this cohort may inform monitoring; leaves open prospective validation of contemporary risk and surveillance.
Observational (n=98)
What is the incidence rate of adverse drug reactions in patients newly treated with amiodarone during long-term follow-up?
Long-term amiodarone therapy is associated with a significant incidence of adverse drug reactions (13.91 per 100 person-years), most commonly thyroid and cardiac events, which occur predominantly in the first 6 months.
Bongard et al. (2006) conducted an observational in Patients newly treated with amiodarone (n=98). Amiodarone was evaluated on Incidence rate of adverse drug reactions (ADRs). In patients newly treated with amiodarone, the overall incidence rate of adverse drug reactions was 13.91 cases per 100 person-years over a mean follow-up of 38 months.
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