Key result
Inherited platelet disorders, such as Glanzmann thrombasthenia and Bernard-Soulier syndrome, provide critical insights into the molecular basis of primary hemostasis and antithrombotic drug development.
Population
Patients with inherited abnormalities of platelets, including Glanzmann thrombasthenia, Bernard-Soulier…
Design
Review
Authors
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May guide antithrombotic targets; leaves open clinical translation pending prospective validation.
Understanding the molecular basis of inherited platelet disorders like Glanzmann thrombasthenia and Bernard-Soulier syndrome has aided in the development of new antithrombotic therapies.
Alan T. Nurden (1999) conducted a review in Inherited platelet disorders. Inherited platelet disorders, such as Glanzmann thrombasthenia and Bernard-Soulier syndrome, provide critical insights into the molecular basis of primary hemostasis and antithrombotic drug development.
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