Right ventricular outflow tract ventriculartachycardia: Detection of previously unrecognized anatomic abnormalities using cine magnetic resonance imaging
Key result
Cine MRI detected right ventricular structural and wall motion abnormalities in 95% of patients with right ventricular outflow tract ventricular tachycardia, compared to 12.5% of normal subjects (p<0.0001).
Why the study?
Right ventricular outflow tract ventricular tachycardia occurs in the absence of apparent structural heart disease, prompting investigation into whether cine MRI can detect unrecognized right ventricular abnormalities.
Population
22 patients with RVOT VT, 16 subjects without structural heart disease, and 44 patients with other cardiovascular diseases
Comparison
Cine MRI findings in RVOT VT vs normal subjects vs other cardiovascular diseases
Design
Cross-sectional comparative study
Authors
Discussion
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Implication
Randomized trial uncovers anatomic abnormalities in patients with ventricular tachycardia, indicating the importance of advanced imaging techniques.
Key Points
- The aim is to identify previously unrecognized anatomic abnormalities in the right ventricular outflow tract associated with ventricular tachycardia.
- Cine magnetic resonance imaging was employed to visualize the right ventricular outflow tract.
- The study focused on patients with diagnosed ventricular tachycardia.
- Anatomical findings were systematically analyzed for abnormalities.
- Identified multiple unrecognized anatomic abnormalities in patients with ventricular tachycardia using cine MRI.
- Demonstrated a significant correlation between these abnormalities and the occurrence of ventricular tachycardia.
Study Design
Type
Cross-Sectional (n=82)
PICO
P
Population
82 subjects including 22 with right ventricular outflow tract ventricular tachycardia, 16 normal subjects, and 44 with other cardiovascular diseases evaluated with cine MRI.
E
Exposure / Comparator
Cine magnetic resonance imaging (MRI) vs Normal subjects / Echocardiography
O
Primary Outcome
Right ventricular structural and wall motion abnormalities, p=< 0.0001
Main Result
Absolute Event Rate: 95% vs 12.5%
p-value: p=< 0.0001
Cite This Study
Carlson et al. (1994) conducted a cross-sectional in Right ventricular outflow tract ventricular tachycardia (n=82). Cine magnetic resonance imaging (MRI) vs. Normal subjects / Echocardiography was evaluated on Right ventricular structural and wall motion abnormalities (p=< 0.0001). Cine MRI detected right ventricular structural and wall motion abnormalities in 95% of patients with right ventricular outflow tract ventricular tachycardia, compared to 12.5% of normal subjects (p<0.0001).