Key result
Frailty, transfusions, and vasopressor use are independently linked to more severe early complications after cardiac surgery.
Why the study?
The study was conducted to identify factors associated with postoperative complications within the first 24 hours among patients undergoing open-heart surgery.
What factors are associated with the severity of postoperative complications within 24 hours of open-heart surgery?
Cross-Sectional (n=192)
No
What factors are associated with the severity of postoperative complications within 24 hours of open-heart surgery?
Frailty, blood transfusion volume, and vasopressor/inotrope support requirements are strong predictors of early postoperative complication severity after open-heart surgery, highlighting areas for targeted perioperative monitoring.
Answers are grounded in this paper and cite their sources.
May inform targeted monitoring in frail high-risk open-heart surgery patients; hypothesis-generating and requires prospective validation before practice change.
AIM: To identify the factors associated with postoperative complications within the first 24 h among individuals who have undergone open-heart surgery. DESIGN: A cross-sectional study. METHODS: The participants were 192 elective open-heart surgery patients admitted to a university hospital in Bangkok, Thailand. Data were collected through data recording forms and questionnaires between August 2023 and February 2024, including the clinical frailty scale health questionnaire, serum creatinine assessment form, systemic immune-inflammation index, vasoactive-inotropic score, Society of Thoracic Surgeons risk score and the comprehensive complication index. Multiple regression was used to analyse the data. RESULTS: Most of the participants (64.06%) were male with an average age of 63.14 (13.22) years. Almost a half of them (45.31%) were diagnosed with coronary artery disease. Frailty, kidney function, inflammation, the amount of packed red cells transfused, vasopressors and inotropes and operative risk were statistically significantly the factors affecting the severity of complications in patients after open-heart surgery during the first 24 h. CONCLUSION: The factors associated with postoperative complications specifically within 24 h after open-heart surgery should be closely monitored, including frailty, kidney function, inflammation, the amount of packed red cells transfused, vasopressors and inotropes and operative risk in order to prevent the postoperative complications. PATIENT OR PUBLIC CONTRIBUTION: All participants contributed to the conducting of this study by participating in a one-day pre-operation and post-operation within 24 h.
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Kamhor et al. (2025) conducted a cross-sectional in Postoperative complications after open-heart surgery (n=192). Patient and perioperative risk factors (frailty, blood transfusion, vasopressors, operative risk) was evaluated on Severity of postoperative complications within the first 24 hours (assessed by Comprehensive Complication Index) (β = 1.90 for frailty; β = 3.22 for packed red cells transfused, p=≤0.001). Frailty, packed red cell transfusions, vasopressor/inotrope use, and higher operative risk were independently associated with increased severity of early complications after open-heart surgery.
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