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March 21, 2006MicrocirculationOpen Access

Endurance exercise training increased arteriolar density in the white and red portions of the gastrocnemius muscle compared to sedentary rats, while interval sprint training had no effect.

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Population

Male Sprague Dawley rats

Comparison

Endurance exercise training or interval sprint… vs Sedentary rats (SED)

Design

Preclinical

Follow-up

10 weeks

Key result

Endurance exercise training increased arteriolar density in the white and red portions of the gastrocnemius muscle compared to sedentary rats, while interval sprint training had no effect.

Authors

MLM. Harold LaughlinJCJohn D. CookRTREBECCA TREMBLE

Discussion

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Overview

Hypothesis-generating for exercise-induced arteriolar remodeling in active muscle; human studies needed before clinical relevance.

Structured PICO

P
Population
Male Sprague Dawley rats subjected to 10 weeks of endurance exercise training or interval sprint training to assess changes in arteriolar density.
I
Intervention
Endurance exercise training (ET) (10 weeks treadmill, 30 m/min, 15% grade, 60 min/day, 5 days/week) or interval sprint training (IST) (10 weeks, six 2.5-min bouts, 4.5-min rest, 60 m/min, 15% incline, 5 days/week)
C
Comparator
Sedentary rats (SED)
O
Outcome
Arteriolar density (number of arterioles/mm2 of tissue) in soleus muscle (S) and red (Gr) and white (Gw) portions of gastrocnemius musclesurrogate

Endurance training, but not interval sprint training, increases arteriolar density in the red and white portions of the gastrocnemius muscle in rats.

Cite This Study

Laughlin et al. (2006) studied this question. Endurance exercise training (ET) and interval sprint training (IST) vs. Sedentary rats (SED) was evaluated on Arteriolar density (number of arterioles/mm2 of tissue) in soleus and gastrocnemius muscles. Endurance exercise training increased arteriolar density in the white and red portions of the gastrocnemius muscle compared to sedentary rats, while interval sprint training had no effect.

synapsesocial.com/papers/6a6aed6e79eb7ca170244775https://doi.org/10.1080/10739680600556829
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Influence of endurance exercise training on distribution of vascular adaptations in rat skeletal muscle1994 · 49 citations
  2. 2Interval sprint training enhances endothelial function and eNOS content in some arteries that perfuse white gastrocnemius muscle2004 · 85 citations
  3. 3Computational Network Model Prediction of Hemodynamic Alterations Due to Arteriolar Remodeling in Interval Sprint Trained Skeletal Muscle2007 · 26 citations
  4. 4Functional adaptations of rat skeletal muscle arterioles to aerobic exercise training1992 · 118 citations
  5. 5Effects of aging and exercise training on skeletal muscle blood flow and resistance artery morphology2012 · 52 citations