Key result
Motor unit number estimation (MUNE) was significantly associated with arm, leg, and global strength in polio survivors over a 15-year period.
Why the study?
Does motor unit number estimation (MUNE) correlate with clinical strength in polio survivors?
Cohort
Does motor unit number estimation (MUNE) correlate with clinical strength in polio survivors?
MUNE correlates with clinical strength in polio survivors, validating its use as a clinically meaningful endpoint in motor neuron disease trials.
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Supports MUNE for monitoring polio survivors; leaves open validation as endpoint in motor neuron disease trials.
Sorenson et al. (2006) conducted a cohort in Polio survivors. Motor unit number estimation (MUNE) was evaluated on Association between MUNE and strength. Motor unit number estimation (MUNE) was significantly associated with arm, leg, and global strength in polio survivors over a 15-year period.
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