Why the study?
Routine electromyography cannot quantitatively analyze motor units, driving rapid development of motor unit number estimation techniques as potential biomarkers in motor neuron disease trials.
This review summarizes electrophysiological techniques for motor unit number estimation (MUNE), highlighting their potential as biomarkers in clinical trials for motor neuron diseases.
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Supports MUNE techniques as potential biomarkers in motor neuron disease; leaves open prospective validation before clinical use.
Murtazina et al. (2018) studied this question.
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