Key result
Acute kidney injury after elective surgery was associated with a significantly increased risk of hospital mortality, with an adjusted odds ratio of 2.57 for Stage 1 AKI compared to no AKI.
Why the study?
Does postoperative AKI increase hospital mortality in adults undergoing elective in-patient surgery?
Cohort (n=36,357)
Yes
Does postoperative AKI increase hospital mortality in adults undergoing elective in-patient surgery?
Odds Ratio: 2.57 (95% CI 1.33–4.96)
Absolute Event Rate: 2.96% vs 0.34%
p-value: p=0.0050
Postoperative AKI severity is strongly associated with increased hospital mortality after elective surgery, while the relationship between preoperative eGFR and mortality depends on age and AKI development.
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Postoperative AKI signals elevated mortality risk; leaves open whether prevention modifies outcomes in elective surgery.
Chaudery et al. (2018) conducted a cohort in Acute Kidney Injury after Elective Surgery (n=36,357). Acute Kidney Injury (Stage 1) vs. No Acute Kidney Injury was evaluated on Hospital mortality (OR 2.57, 95% CI 1.33-4.96, p=0.0050). Acute kidney injury after elective surgery was associated with a significantly increased risk of hospital mortality, with an adjusted odds ratio of 2.57 for Stage 1 AKI compared to no AKI.
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