What question did this study set out to answer?

This research aims to evaluate the long-term outcomes of abdominal aortic aneurysm repair using first-generation stent grafts.

January 1, 2007Archives of Surgery

Long-term Results of Endovascular Abdominal Aortic Aneurysm Treatment With the First Generation of Commercially Available Stent Grafts

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Abdominal aortic aneurysm (n=1190). Intervention: Endovascular abdominal aortic aneurysm repair with first-generation stent grafts. Primary outcome: Combined outcome event (conversion-free and rupture-free survival) after 8 years.

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Key result

Endovascular abdominal aortic aneurysm repair with first-generation stent grafts resulted in an 8-year cumulative conversion-free and rupture-free survival of 48.0%.

Why the study?

What are the long-term outcomes and complication rates of elective endovascular abdominal aortic aneurysm repair using first-generation stent grafts?

Key Points

This research aims to evaluate the long-term outcomes of abdominal aortic aneurysm repair using first-generation stent grafts.
Multicenter registry analysis from 62 European centers with 1190 patients
Follow-up duration of up to 8 years analyzing morbidity and mortality rates
Use of life-table analyses and multivariate Cox proportional hazards models for survival analysis
Conversion to open repair occurred in 7.1% of patients, with aneurysm rupture in 2.4%.
Overall mortality rate was 19.9%, with aneurysm-related death at 3.0%.
Cumulative conversion-free and rupture-free survival rate after 8 years was 48.0%

Study Design

Type

Observational (n=1,190)

Multicenter

Yes

Structured PICO

What are the long-term outcomes and complication rates of elective endovascular abdominal aortic aneurysm repair using first-generation stent grafts?

Population

1,190 patients who underwent elective endovascular abdominal aortic aneurysm repair with a first-generation stent graft, followed for up to 8 years.

Exposure

Elective endovascular abdominal aortic aneurysm repair with first-generation stent grafts (Stentor or Vanguard)

Outcome

Morbidity and mortality (conversion to open repair, aneurysm rupture, all-cause death, and aneurysm-related death)hard clinical

Patients treated with first-generation stent grafts for abdominal aortic aneurysms have a considerable risk of late complications, highlighting the need for lifelong surveillance.

Limitations

How these findings translate to the outcome of newer-generation stent grafts is unknown.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Warrants lifelong surveillance after first-generation EVAR; leaves open durability of modern stent grafts.

Cite This Study

Lina J. Leurs (2007) conducted an observational in Abdominal aortic aneurysm (n=1,190). Endovascular abdominal aortic aneurysm repair with first-generation stent grafts was evaluated on Combined outcome event (conversion-free and rupture-free survival) after 8 years. Endovascular abdominal aortic aneurysm repair with first-generation stent grafts resulted in an 8-year cumulative conversion-free and rupture-free survival of 48.0%.

synapsesocial.com/papers/6a6af39679eb7ca1702448c4 https://doi.org/10.1001/archsurg.142.1.33

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Long-term Results of Endovascular Abdominal Aortic Aneurysm Treatment With the First Generation of Commercially Available Stent Grafts

Key Points

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Long-term Results of Endovascular Abdominal Aortic Aneurysm Treatment With the First Generation of Commercially Available Stent Grafts

Key Points

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Also Consider