Short-term results of endovascular thoracoabdominal aortic repair with multi-branched stent-graft: a systematic review and meta-analysis over the last 5 years

Endovascular repair with multi-branched stent-graft is a common method for thoracoabdominal aortic aneurysms. Objective. To perform a systematic review and meta-analysis of short-term results (30 days) after endovascular treatment of thoracoabdominal aortic aneurysms withmulti-branched stent-graft device in the studies published in the last 5 years. Material and methods. Baseline searching in the PubMed (Medline) database identified 79 studies. Seven articles were included in systematic review. Results. Technical success rate for multi-branched stent-graft was 95.7% (95% CI 93.9—97.5, I2=46%, p=0.085). Incidence of access-related complications was 15.9% (95% CI 13.3—18.5). Type 1 endoleak occurred in 2.6% (95% CI 1.2—3.9), type 3 endoleak — 4% of cases (95% CI 2.4—5.7). Spinal cord ischemia was observed in 13.7% (95% CI 10.7—16.8), paraplegia — in 5.2% (95% CI 3.8—6.5). Post-intervention hemodialysis was necessary in 5.9% of cases (95% CI 4.6—7.3). Repeated interventions were performed in 15.7% of cases (95% CI 8.5—22.9). Mortality rate was 9.9% (95% CI 4.8—14.9) with high heterogeneity (I2=88%, p<0.001). Conclusion. We found high technical success rate, acceptable complication rate and low mortality in early period. It is necessary to study the long-term results.