What question did this study set out to answer?

This study aims to evaluate the association between quick sequential organ failure assessment (qSOFA) and 28-day mortality in ICU patients with sepsis.

January 23, 2024Critical CareOpen Access

Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings

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Authors

ALAndrew LiNational University of Singapore LLLowell LingChinese University of Hong Kong HQHanyu QinCentre for Human Genetics

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Implication

Secondary analysis associates qSOFA with 28-day mortality in ICU sepsis patients, highlighting income disparities.

Key Points

This study aims to evaluate the association between quick sequential organ failure assessment (qSOFA) and 28-day mortality in ICU patients with sepsis.
Conducted a secondary analysis of 4980 patients from the MOSAICS II study on sepsis in Asian ICUs.
Assessed associations between qSOFA scores at ICU admission and mortality across different income settings.
Utilized modified Poisson regression to calculate the adjusted relative risk (RR) of qSOFA on mortality.
Higher qSOFA scores correlated with increased 28-day mortality in low and lower middle income (p < 0.001) and upper middle income (p < 0.001) countries, but not in high income (p = 0.220).
qSOFA remained independently associated with 28-day mortality (adjusted RR 1.09, 95% CI 1.00-1.18, p = 0.038) after adjusting for confounding factors.
3-day mortality was significantly associated with higher qSOFA scores across all income settings (p < 0.001).

Cite This Study

Li et al. (2024) studied this question.

synapsesocial.com/papers/6a6af9302ef98b0efacb4424 https://doi.org/10.1186/s13054-024-04804-7

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Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings

Discussion

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Implication

Key Points

Cite This Study

Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings

Discussion

Member takes

Implication

Key Points

Cite This Study

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