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Shows ghrelin gene effects on fat accumulation in women, suggesting potential obesity treatments.
Hormones encoded by the ghrelin gene, GHRL , regulate many body systems. Here, we show that GHRL is abundant in monocytes. Analysis of women subjected to bariatric surgery revealed a significant postoperative reduction of GHRL in monocytes. We hypothesise that GHRL mediates monocyte-adipocyte cross-talk in health and obesity.
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Seim et al. (2017) studied this question.
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