Key result
Patients with EV71 infection and pulmonary edema had dramatically varied blood values, including IL-6, compared to those without pulmonary edema.
Population
24 patients with Enterovirus 71 infection involving diverse manifestations or complications, including…
Design
Cohort
Authors
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IL-6 elevation may flag high-risk EV71 cases; hypothesis-generating for anti-inflammatory strategies but should not change practice.
Observational (n=24)
The combination of CNS and systemic inflammatory response, marked by elevated IL-6, may trigger EV71-related cardiopulmonary collapse.
Lin et al. (2003) conducted an observational in Enterovirus 71 (EV71) infection (n=24). Pulmonary edema vs. No pulmonary edema was evaluated on Cerebrospinal fluid (CSF) and serum levels of IL-6 and IL-1beta. Patients with EV71 infection and pulmonary edema had dramatically varied blood values, including IL-6, compared to those without pulmonary edema.
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