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Recent developments in diagnostic, prognostic, and therapeutic strategies for abdominal aortic aneurysm highlight the need for large prospective studies to validate new management pathways.
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This review highlights the need for large prospective imaging, biomarker, and intervention studies to validate new management pathways for abdominal aortic aneurysm.
PURPOSE OF REVIEW: Abdominal aortic aneurysm (AAA) is being diagnosed more frequently in older patients due to the increased use of abdominal imaging and the rising average age of western populations. Currently the management of this condition has two important deficiencies: inadequate methods to identify AAAs at risk of progression and rupture and the current lack of effective nonsurgical therapies. In this review recent developments in identifying new diagnostic, prognostic and therapeutic strategies for AAA are discussed. RECENT FINDINGS: There are growing number of animal and human association studies which have identified markers and strategies of potential value in improving identification, monitoring and treatment of AAA. SUMMARY: Selective large prospective imaging, biomarker and intervention studies are now required to clearly demonstrate the value of new management pathways for AAA.
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Golledge et al. (2009) conducted a review in Abdominal aortic aneurysm. Recent developments in diagnostic, prognostic, and therapeutic strategies for abdominal aortic aneurysm highlight the need for large prospective studies to validate new management pathways.
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