Key result
In anesthetized dogs, the induction of renal ischemia abolished the renal vasoconstrictor activity of angiotensin II, resulting in a significant increase in renal blood flow from 72 to 120 ml/min.
Authors
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Absolute Event Rate: 120% vs 72%
p-value: p=<0.001
McGiff et al. (1964) studied Renal ischemia (experimental) (n=26). Angiotensin II vs. Pre-ischemia control was evaluated on Renal blood flow (ml/min) during renal ischemia (p=<0.001). In anesthetized dogs, the induction of renal ischemia abolished the renal vasoconstrictor activity of angiotensin II, resulting in a significant increase in renal blood flow from 72 to 120 ml/min.
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