Key result
Compared with men, women demonstrated significantly greater peak left ventricular wall stress (471.9 vs 412.5 kdynes/cm2) at similar levels of cuff-measured blood pressure.
Why the study?
Do women have greater left ventricular wall stress than men at the same level of cuff-measured blood pressure?
Cross-Sectional (n=990)
No
Do women have greater left ventricular wall stress than men at the same level of cuff-measured blood pressure?
Absolute Event Rate: 471.9% vs 412.5%
p-value: p=<0.001
Women experience higher left ventricular afterload than men at identical cuff-measured blood pressures, suggesting non-sex-specific blood pressure targets may disproportionately increase heart failure risk in women.
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Women may face higher HF risk at standard BP targets; leaves open need for sex-specific thresholds.
Lü et al. (2023) conducted a cross-sectional in Apparently healthy adults (n=990). Female sex vs. Male sex was evaluated on Systolic peak left ventricular wall stress (Ó-peak) in kdynes/cm2 (p=<0.001). Compared with men, women demonstrated significantly greater peak left ventricular wall stress (471.9 vs 412.5 kdynes/cm2) at similar levels of cuff-measured blood pressure.
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