Key result
The NeoChord echo-guided transapical beating heart repair procedure achieved a patient success rate of 91.2% at one year and 81.2% at three years in patients with severe degenerative mitral regurgitation.
Why the study?
The NeoChord echo-guided transapical beating heart repair is a promising minimally invasive surgical procedure for degenerative mitral regurgitation correction, with techniques improving through procedure standardization and patient selection.
Population
Two hundred and three consecutive patients with severe symptomatic DMR due to prolapse or flail
Comparison
NeoChord procedure outcomes categorized by MV anatomy (Type A, B, C, D)
Design
Single-center observational cohort study
Follow-up
Median 24 months [interquartile range, 9-36]
Authors
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Hypothesis-generating for transapical mitral repair; randomized trials needed before practice adoption.
Observational (n=203)
No
Transapical off-pump echo-guided mitral valve repair with neochordae implantation demonstrates good mid-term clinical success and sustained reverse remodeling up to three years in patients with severe degenerative mitral regurgitation.
Gerosa et al. (2021) conducted an observational in Severe symptomatic degenerative mitral valve regurgitation (n=203). NeoChord echo-guided transapical beating heart repair was evaluated on Patient success (composite of procedural success and freedom from death, stroke, MR > moderate, unplanned interventions, cardiac rehospitalization, or worsening NYHA class). The NeoChord echo-guided transapical beating heart repair procedure achieved a patient success rate of 91.2% at one year and 81.2% at three years in patients with severe degenerative mitral regurgitation.
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