Key result
Transapical off-pump mitral valve repair with NeoChord implantation is a reproducible and safe technique for treating eligible patients with chronic severe degenerative mitral regurgitation.
Transapical off-pump mitral valve repair with NeoChord implantation is described as a reproducible and safe approach for eligible patients with chronic severe degenerative mitral regurgitation.
May warrant consideration in select high-risk patients; leaves open need for RCTs on durability and outcomes.
Transapical off-pump mitral valve repair (MVr) with NeoChord implantation has become widely applied in Europe for patients presenting with severe mitral regurgitation due to leaflet prolapse or flail. The procedure is performed under real-time 2D- and 3D-transesophageal echocardiography (TEE) for both implantation and neochordae tension adjustment allowing real-time monitoring of hemodynamic recovery. Preoperative anatomic and echocardiographic selection criteria, procedure refinement, as well as innovative ex-vivo surgical simulator training have been developed and strategically employed in the past few years, to generate a robust precision-based procedural framework with significantly enhanced operator use, patient safety and clinical outcomes. The procedure has evolved into a reproducibly successful and safe approach, which complements existing surgical treatment strategies available to eligible patients with chronic severe degenerative mitral regurgitation.
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Colli et al. (2018) conducted a review in Severe degenerative mitral regurgitation. Transapical off-pump mitral valve repair with NeoChord implantation was evaluated. Transapical off-pump mitral valve repair with NeoChord implantation is a reproducible and safe technique for treating eligible patients with chronic severe degenerative mitral regurgitation.
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