Key result
Dipping tobacco use significantly decreased low frequency power of heart rate variability (383.8 vs 952.8 ms2) and increased diastolic blood pressure compared to non-users.
Why the study?
Does dipping tobacco use alter cardiovascular autonomic function as measured by heart rate variability and blood pressure in males?
Cross-Sectional (n=60)
No
Does dipping tobacco use alter cardiovascular autonomic function as measured by heart rate variability and blood pressure in males?
Absolute Event Rate: 383.8% vs 952.8%
p-value: p=<0.01
Dipping tobacco use is associated with altered cardiovascular autonomic function, including reduced sympathetic control and increased diastolic blood pressure, suggesting it is harmful to cardiovascular health.
Hypothesis-generating for autonomic and BP effects of dipping tobacco; prospective studies needed before clinical implications.
Background: WHO (2010) reported the rise in the number of smokeless tobacco users in India. Dipping tobacco is a form of smokeless tobacco being used in these region in various trade names. Nicotine in smoking tobacco is found to alter the cardiovascular autonomic functions. As the expected cardiovascular mortality due to tobacco use across the globe is very high, here we studied the effect of dipping tobacco on cardiovascular autonomic function using the short term heart rate variability (HRV) analysis. Methods: Five minutes Lead II ECG at rest is aquired from male dipping tobacco moderate users (n=30) and age matched controls (n=30). Frequency and time domain parameters were derived and analysed using the Kubios HRV analysis software. Blood pressure changes were also compared. Unpaired ‘t’ test was done using SPSS 17.0 and statistical significance was set at p<0.05. Results: Significant changes in certain parameters indicated that there is a developing set back in the sympathetic control over the heart (LF, 383.8+115.8, 952.8+131.1, p<0.01) and also an established increase in diastolic blood pressure (73.1+2.8, 65.48+1.5, p<0.01). Conclusion: Dipping tobacco a form of smokeless tobacco is equally harmful like any smoked tobacco in altering the cardiovascular autonomic function. Thereby the increase in smokeless tobacco users in India or any country is going to add up more to the mortality rate due to tobacco related diseases in near future as estimated by WHO. An immediate measure to stop the production, sale and use of these smokeless tobacco products could curb this menace. Asian Journal of Medical Science, Volume-5(3) 2014: 91-94 http://dx.doi.org/10.3126/ajms.v5i3.9588
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Mohesh et al. (2014) conducted a cross-sectional in Dipping tobacco use (n=60). Dipping tobacco vs. No tobacco use was evaluated on Low frequency (LF) power (ms2) (p=<0.01). Dipping tobacco use significantly decreased low frequency power of heart rate variability (383.8 vs 952.8 ms2) and increased diastolic blood pressure compared to non-users.
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