Key result
Iatrogenic atrial septal defects following MitraClip therapy are common and, despite potential acute left atrial pressure relief, persistent defects are associated with significant shunting and worse clinical outcomes.
Why the study?
What are the haemodynamic and functional consequences of persisting iatrogenic atrial septal defect following MitraClip therapy, and should it be closed?
What are the haemodynamic and functional consequences of persisting iatrogenic atrial septal defect following MitraClip therapy, and should it be closed?
This review highlights that while iatrogenic atrial septal defects after MitraClip can relieve left atrial pressure, their persistence is linked to worse clinical outcomes, suggesting a potential benefit for closure in selected patients.
No takes yet. Share an insight, caveat, or question.
May warrant iASD surveillance after MitraClip; leaves open whether closure improves outcomes.
Hart et al. (2016) conducted a review in Severe mitral regurgitation requiring MitraClip therapy. Iatrogenic atrial septal defect following MitraClip therapy was evaluated. Iatrogenic atrial septal defects following MitraClip therapy are common and, despite potential acute left atrial pressure relief, persistent defects are associated with significant shunting and worse clinical outcomes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: