Why the study?
Does a persistent iatrogenic atrial septal defect following MitraClip affect hemodynamic compromise or prognosis compared to no residual defect in patients undergoing TEER?
Does a persistent iatrogenic atrial septal defect following MitraClip affect hemodynamic compromise or prognosis compared to no residual defect in patients undergoing TEER?
Persistent iatrogenic atrial septal defects after TEER appear safe in the mid-term, arguing against the routine need for interventional closure.
May support deferring routine iASD closure post-TEER; leaves open need for prospective confirmation.
Notwithstanding higher RV pressures, patients with persistent iASD had no hemodynamic compromise and an equal prognosis compared with those without a residual atrial defect after a TEER procedure. These findings support the mid-term safety of procedures in which an interatrial defect needs to be created and would argue against the need for interventional closure.
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Chao et al. (2022) studied this question.
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