Key result
Dual drug therapy was the most prevalent antihypertensive regimen (46%), followed by monotherapy (34%), with calcium channel blockers being the most frequently prescribed drug class.
Why the study?
The study was conducted to evaluate the prescribing patterns of antihypertensive drugs and observe disparities between actual clinical practice and recommended pharmacological treatments at a secondary care hospital.
Observational (n=200)
No
In this secondary care hospital in Tamilnadu, dual combination therapy (particularly CCB + ARB) was the most common prescribing pattern for hypertension.
Informs local prescribing audits in secondary care; leaves open whether these patterns optimize outcomes in broader populations.
Background: Hypertension is the most common alterable risk factor for cardiovascular disease, stroke and renal failure. Drug utilization study facilitate the rational use of drugs and provides an in sign into the use of drugs pattern, as such the present study. Was conducted to evaluate the prescribing patterns of antihypertensive drugs and to observe the disparity between the actual practices and recommended for pharmacological treatments of hypertension at a secondary care hospital. Methods: Retrospective study conducted over a period of six months. Case records of hypertension cases from January 2021 to July 2022 cases reported to the department of medicine. Results: Total 200 patients of hypertension cases included in this study, 53 % were male and 37 % were females with a large portion of hypertension patients 41% in the age group above 70 years. During study period, it was observed that hypertensive patients 62 (31%) more due to smoking. Diabetes mellitus 41 (21%) and angina 27 (14%) were the most common comorbidities in our hypertensive patients. Prevalence of dual drug combination was the highest 46% followed by monotherapy 34%. , most frequently prescribed drug class was calcium channel blockers for 30 (15 %) hypertensive patients prescribed class in monotherapy, in dual therapy, combinations of antihypertensive drugs were prescribed among which the combination of CCBs with ARBs was prescribed the most 14.5%, whereas prescription of combination of CCB, Beta blocker and Diuretics was prescribed the most 7.5% in triple drug therapy. Conclusion: This present study provides an overview on drug utilization of antihypertensive in one of the secondary care hospitals in tamilnadu. In this study, the majority of medications used as monotherapy are calcium channel blockers. The most often given medications for combination therapy include calcium channel blockers with beta blockers and diuretics with Angiotensin receptor blockers.
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Anandharaj et al. (2022) conducted an observational in Hypertension (n=200). Antihypertensive drugs was evaluated on Prescribing patterns of antihypertensive drugs. Dual drug therapy was the most prevalent antihypertensive regimen (46%), followed by monotherapy (34%), with calcium channel blockers being the most frequently prescribed drug class.
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