September 1, 2001Current Opinion in Nephrology & Hypertension
Nocturnal non-dipping: what does it augur?
Key result
The nocturnal non-dipping pattern of blood pressure occurs in about 25% of hypertensives and appears to predict the progression of renal disease and increased cardiovascular morbidity.
Population
Hypertensive patients, specifically those with a non-dipping blood pressure pattern
Design
Review
Authors
Discussion
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Implication
Non-dipping BP may warrant closer monitoring in diabetics and renal patients; leaves open targeted interventions on sleep and sympathetic activity.
Structured PICO
P
Population
Hypertensive patients, specifically those with a non-dipping blood pressure pattern (defined as a nocturnal fall of less than 10%)
The non-dipping blood pressure pattern is associated with adverse cardiovascular and renal outcomes, though the therapeutic consequences of normalizing it remain unknown.
Limitations
- In patients with uncomplicated hypertension, the reproducibility is relatively low.
- The therapeutic consequences of normalizing the non-dipping pattern are unknown.
Cite This Study
Pickering et al. (2001) conducted a review in Hypertension. Nocturnal non-dipping pattern of blood pressure was evaluated. The nocturnal non-dipping pattern of blood pressure occurs in about 25% of hypertensives and appears to predict the progression of renal disease and increased cardiovascular morbidity.