Key result
Transesophageal echocardiography detected a left atrial appendage thrombus in a 68-year-old man with atrial fibrillation on rivaroxaban 20 mg/day, suggesting interference with oxcarbazepine.
Case Report (n=1)
This case highlights the utility of TEE prior to elective cardioversion in patients with AF and hypokinetic cardiomyopathy on NOACs, especially when potential drug interactions (e.g., oxcarbazepine) exist.
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May prompt TEE before cardioversion in AF on NOACs with interacting drugs; hypothesis-generating for oxcarbazepine-rivaroxaban interaction.
Serra et al. (2015) conducted a case report in permanent atrial fibrillation (n=1). Rivaroxaban was evaluated on Left atrial appendage thrombus. Transesophageal echocardiography detected a left atrial appendage thrombus in a 68-year-old man with atrial fibrillation on rivaroxaban 20 mg/day, suggesting interference with oxcarbazepine.
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