March 1, 1989The Journal of Infectious Diseases
Viruses Can Cause Disease in the Absence of Morphological Evidence of Cell Injury: Implication for Uncovering New Diseases in the Future
Key result
Viruses can cause systemic diseases by altering the cellular production of hormones, neurotransmitters, and lymphokines without causing detectable morphological cell destruction.
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Implication
Viral effects on specialized cell products may drive non-cytopathic systemic disease; leaves open cardiovascular homeostasis implications.
Key Points
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Cite This Study
Michael B. A. Oldstone (1989) studied this question. Viruses can cause systemic diseases by altering the cellular production of hormones, neurotransmitters, and lymphokines without causing detectable morphological cell destruction.