Key result
In patients with heart failure, self-care maintenance moderated the indirect beneficial effect of social support on health-related quality of life through reduced depressive symptoms and anxiety.
Why the study?
Mechanisms underlying the associations between depressive symptoms, anxiety, inadequate social support, and HRQoL in heart failure are unknown, and whether self-care maintenance moderates these relationships was undetermined.
Does self-care maintenance moderate the effect of social support on HRQoL through psychological status in patients with heart failure?
Cross-Sectional (n=167)
Does self-care maintenance moderate the effect of social support on HRQoL through psychological status in patients with heart failure?
Higher social support improves health-related quality of life in heart failure patients by reducing depressive symptoms and anxiety, an effect that is more profound with higher levels of self-care maintenance.
Self-care maintenance may indirectly shape HRQoL pathways in HF; leaves open causal effects and needs prospective trials before practice change.
BACKGROUND: Depressive symptoms, anxiety, and inadequate social support are predictors of health-related quality of life (HRQoL) in persons with heart failure, but the prediction of HRQoL is multifaceted, and mechanisms underlying association are unknown. Self-care maintenance may moderate associations among these predictors, which is essential to better heart failure outcomes. OBJECTIVES: To determine whether self-care maintenance moderates the direct and indirect effects of social support on HRQoL through psychological status (i.e., depressive symptoms and anxiety) in persons with heart failure. METHODS: We conducted a secondary analysis using cross-sectional data collected from 167 participants. Participants completed Patient Health Questionnaire-9, Brief Symptom Inventory, Multidimensional Scale of Perceived Social Support, Self-Care of Heart Failure Index version 6.2, and Minnesota Living with Heart Failure Questionnaire for depressive symptoms, anxiety, social support, self-care maintenance, and HRQoL, respectively. PROCESS macro was used for the analysis. RESULTS: Self-care maintenance did not moderate the direct effect of social support on HRQoL. However, self-care maintenance moderated the indirect effect of social support on HRQoL through depressive symptoms and anxiety. The beneficial effect of social support on depressive symptoms and anxiety varied with self-care maintenance, suggesting a dose-response moderation effect. DISCUSSION: Findings suggest that an increment in social support reduces depressive symptoms and anxiety, which further improves HRQoL. This relationship was more profound when the self-care maintenance was at a higher level. Our study emphasizes the need to focus on improving HRQoL by promoting positive social support that can decrease depressive symptoms and anxiety in persons with heart failure-particularly in those with low or moderate levels of self-care maintenance.
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Thapa et al. (2025) conducted a cross-sectional in heart failure (n=167). Social support was evaluated on Health-related quality of life (HRQoL). In patients with heart failure, self-care maintenance moderated the indirect beneficial effect of social support on health-related quality of life through reduced depressive symptoms and anxiety.
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